Park Holme is a south-western suburb of Adelaide in the City of Marion, South Australia, located about 8 km (5 mi) from the Adelaide city centre. It is bordered to the east by Marion Road, to the west by Hendrie Street, to the south by Oaklands Road, and to the north by Tarranna Ave, which is just south of Bray Street. It is adjacent to Ascot Park, Edwardstown, South Plympton, Mitchell Park, Clovelly Park, Glengowrie, Morphettville and Oaklands Park. Park Holme covers 115 hectares (280 acres), (1.15 sq km).

Two bus routes service the suburb directly: the M44 runs from Golden Grove in the north-eastern suburbs through the city centre, through Ascot Park and its adjoining suburbs to Westfield Marion and the 248 turns off Marion Road at Plympton Park and travels along Hendrie Street until Oaklands Road, stopping outside the Marion Swimming Centre.