Port Melbourne is an inner-city suburb in Melbourne, Victoria, Australia, 3 km (2 mi) south-west of the Melbourne central business district, located within the Cities of Melbourne and Port Phillip local government areas. Port Melbourne recorded a population of 17,633 at the 2021 census.

In the 2016 census, there were 16,175 people in Port Melbourne. 63.2% of people were born in Australia. The next most common countries of birth were England 5.4%, New Zealand 2.6%, Greece 2.0%, United States of America 1.0% and Italy 1.0%. 72.3% of people spoke only English at home. Other languages spoken at home included Greek 4.8%, Italian 1.7%, Mandarin 1.3%, French 0.8% and Russian 0.8%. The most common responses for religion were No Religion 38.3% and Catholic 21.8%.

Two major freeways run through Port Melbourne; the West Gate Freeway, which runs east–west from the West Gate Bridge and CityLink, which runs north toward the Bolte Bridge. Other main roads include Bay Street, Williamstown Road, Lorimer Street (which runs along the Yarra River), Graham Street, Salmon Street, Inglis Street and Beach Street (which runs toward Beaconsfield Parade and St Kilda). Port Melbourne’s roads are a mix of planning styles and as a result can be difficult to navigate.