Colo Vale is a Northern Village of the Southern Highlands of New South Wales, Australia, in Wingecarribee Shire. Colo Vale is approximately 100 km south west on the Hume Highway from Sydney. It is situated 2 km north-west of Aylmerton, 5 km from the Hume Highway and 12 km drive to Mittagong. The surrounding area is part of the Parish of Colo which includes the villages of Aylmerton, Willow Vale, Alpine and Yerrinbool. Colo Vale has a mixed-business general store and many home-based businesses, including hairdressers, small manufacturing businesses and a large native plant nursery (Wariapendi Nursery) and a Public School on Wattle Street. A large sporting oval is located adjacent to the school with tennis courts, a community hall and a Rural Fire Service station.