Port Germein is a small sea-side town in the Australian state of South Australia located about 219 kilometres (136 mi) north of the state capital of Adelaide and about 19 kilometres (12 mi) north of the city of Port Pirie on the eastern side of South Australia’s Spencer Gulf overlooking Germein Bay. Port Germein was named after Samuel Germein, who moved into the territory in 1840, although some credit his brother John to be the first European to traverse the area. The township was proclaimed in 1878. Port Germein’s population in the 2006 census was 249.

The Augusta Highway and the Adelaide-Port Augusta railway line both pass the east side of the township. The railway line has an 1800m passing loop and a goods siding was commissioned in 2015 and is operated by SCT Logistics.