Sandleton is a locality and former town in South Australia. It is located on the plains on the eastern side of the Mount Lofty Ranges. The current boundaries for the locality were created in 2003 for the long-established name of the area.

The main route through the locality is Halfway House Road which runs from the Sturt Highway through Annadale and Sandleton to Sedan. It is part of the heavy vehicle detour route D1 used if either the Blanchetown Bridge or Swanport Bridge over the Murray River are unavailable for an extended time, or part of the South Eastern Freeway. This road is also part of the route from Murray Bridge to Burra with potential for the route to be upgraded to become a road freight bypass of Adelaide.