Chiltern is a town in Victoria, Australia, in the northeast of the state between Wangaratta and Wodonga, in the Shire of Indigo. At the 2021 census, Chiltern had a population of 1,580. It is the birthplace of Prime Minister John McEwen. The town is close to the Chiltern-Mount Pilot National Park. Chiltern was once on the main road between Melbourne and Sydney but is now bypassed by the Hume Freeway running one kilometre to the south.

The railway station on the North East railway line, has V/Line services running between Melbourne and Albury.